From Milan: motorway A1 Milano-Bologna-Firenze-Roma, exit at Valdichiana, follow the indication towards Montepulciano.

From Rome: motorway A1 until Firenze, exit at Chiusi-Chianciano Terme, follow the indication to Montepulciano.

Airport Leonardo Da Vinci – Roma Fiumicino.
Airport A.Vespucci, Florence.

Airport G. Galilei, Pisa.
Airport Roma Ciampino.